His work has been funded by the NIH. Network. The effect of the demyelinating agent cuprizone on binge-like eating of sweetened palatable food in female and male C57BL/6 substrains. View All. This work has resulted in widely used tools and algorithms for profiling transcription factors (MAT, MA2C), preprocessing and integrating of genomic data (ComBat, BatchQC, SCAN-UPC), aligning sequencing reads (GNUMAP), developing multi-gene biomarker signatures (ASSIGN), and metagenomic profiling (PathoScope). Born on November 23, 1948, Evan L Johnson has already turned or will soon turn 71. Manabe YC, Andrade BB, Gupte N, Leong S, Kintali M, Matoga M, Riviere C, Sameneka W, Lama JR, Naidoo K, Zhao Y, Johnson WE, Ellner JJ, Hosseinipour MC, Bisson GP, Salgame P, Gupta A. Package ‘sva’ January 20, 2021 Title Surrogate Variable Analysis Version 3.38.0 Author Jeffrey T. Leek , W. Evan Johnson , They are actively developing methods and software tools for data preprocessing, integration, and downstream analysis, and applying these tools in a variety of clinical and biomedical applications. Cheers, Santana Boston University. 2020 Jul; 34(7):9223-9244. Artifacts in the scRNA-seq data, such as doublets or ambient RNA, can also hinder downstream clustering and marker selection and need to be assessed. Division of Pulmonary and Critical Care Medicine, Boston University School of Medicine. M.A. Ph.D in Biostatistics, Harvard University M.A. PMID: 32936872. PMID: 31695961. Bioinformatics students David Jenkins and Eric Reed's Research in BU Today Bioinformatics PhD students David Jenkins, and Eric Reed's work with Profs. Each level of such a hierarchy is composed of different subunits which cooperate to perform distinct biological functions. Full Member, Boston Nutrition Obesity Research Center, Boston University Medical Center. All rights reserved. They have also lived in Lenexa, KS and South Abington Township, PA. Evan is related to Russell D Johnson and Pam Johnson as well as 3 additional people. First Quarter. The impact of batch effects can be severe, potentially completely compromising bi… View Evan Johnson’s profile on LinkedIn, the world's largest professional community. Title Associate Professor of Medicine and Biostatistics; Office E609; Email wej@bu.edu; Phone 617-358-7048; Education B.S., Summa Cum Laude, Mathematics, Southern Utah University, Cedar City, Utah, 2002 M.S., Statistics, Brigham Young University, Provo, Utah, 2003 2019 Nov 25. William Evan Johnson PhD Associate Professor, Computational Biomedicine Associate Professor, Biostatistics 72 East Concord Street | (617) 638-2541. wej@bu.edu PMID: 32071385. in Biostatistics, Harvard University … ... 12.11 BU Sec Seminar: “Network Security for Cryptocurrency” Hariri Institute for Computing111 Cummington Mall, Boston, MA 02215. B.S. View Evan Johnson’s profile on LinkedIn, the world’s largest professional community. 2020 07 01; 150:104678. View 69 more publications:View Full Profile at BUMC, Get the latest from Boston University School of Public Health, © Boston University. in Biostatistics, Harvard University Associate Professor of Medicine and Biostatistics. W Evan Johnson. M.S. This work was funded in part by CRDF grant #61407, NIH grant 5U19 AI111276-05NSF, NSF grant DBI-1559829 (awarded to the Boston University Bioinformatics BRITE REU program), Evan has 8 jobs listed on their profile. William Johnson specializes in computational biology and biostatistics, developing new tools to investigate disease prognoses and causes and to help determine effective regimens based on individual patients’ risk factors. The Official Athletics Site for the University of Washington. 2020 Feb 18. Ikezu S, Yeh H, Delpech JC, Woodbury ME, Van Enoo AA, Ruan Z, Sivakumaran S, You Y, Holland C, Guillamon-Vivancos T, Yoshii-Kitahara A, Botros MB, Madore C, Chao PH, Desani A, Manimaran S, Kalavai SV, Johnson WE, Butovsky O, Medalla M, Luebke JI, Ikezu T. Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities. Mol Psychiatry. Member, Evans Center for Interdisciplinary Biomedical Research, Boston University. Evan is the Co-Director of the Single Cell Sequencing Core, and serves in the following capacities as well: Ph.D in Biostatistics, Harvard University 2020 01; 120:101898. These goals are complicated by the presence of latent variables or unwanted heterogeneity in the high-throughput data. Cited. Eric Kolaczyk. (7 replies) Hi, How is it possible to judge whether there is any batch effect in two groups of Affymetrix .cel files ? Full lists of Evan’s publications can be found on Google Scholar and MyNCBI. Faits T, Walker ME, Rodriguez-Morato J, Meng H, Gervis JE, Galluccio JM, Lichtenstein AH, Johnson WE, Matthan NR. PMID: 32209386. View Profile . David Dinges. 2019 Sep 05; 19(1):881. https://www.bumc.bu.edu/compbiomed/people/faculty/w-evan-johnson Select this result to view Evan M Johnson… For faster response, email W. Evan Johnson at bioconductor@r-project.org, add "ComBat" to subject line, and cc "wevanjohnson@gmail.com" Trends Cancer. BMC Cancer. 5' UTR variants in the quantitative trait gene Hnrnph1 support reduced 5' UTR usage and hnRNP H protein as a molecular mechanism underlying reduced methamphetamine sensitivity. Second Quarter. Ehab Billatos. The Johnson lab studies the human microbiome, i.e., microbial communities which live in and on the human body and play a vital role in health and disease. 2019 Oct; 9(10):215-226. Decontamination of ambient RNA in single-cell RNA-seq with DecontX. W Evan Johnson ... Z. when she was affiliated with the Division of Computational Biomedicine and the Graduate Program in Bioinformatics at Boston University. Visit Back2BU for the latest updates and information on BU's response to COVID-19. Sarah Mazzilli. W. Evan Johnson (Boston University) Multiomic Biomarker Validation April 29, 2013 10 / 25. Performing comprehensive quality control is necessary to remove technical or biological artifacts in single-cell RNA sequencing (scRNA-seq) data. The department also hosts an annual lecture by a distinguished statistician in honor of … Watch game highlights of Washington Huskies games online, get tickets to Huskies athletic events, and shop for official Washington Huskies gear in the team store. Yang S, Corbett SE, Koga Y, Wang Z, Johnson WE, Yajima M, Campbell JD. PMID: 32101723. tikezu@bu.edu. Evan Johnson. Visit Back2BU for the latest updates and information on BU's response to COVID-19. Batch effects are the most widely recognized potential latent variable in genomic experiments. PMID: 32090859. Cathie Jo Martin. Electrical & Computer Engineering, ENG. Tuberculosis (Edinb). 2020 12 10; 112(6):1631-1641. Evan Johnson. Pathway activity profiling of growth factor receptor network and stemness pathways differentiates metaplastic breast cancer histological subtypes. North 6 0 0 0—6. Thanks to Evan Johnson for his continual support and guidance, and Gary Benson for inviting me to be a part of the BRITE REU. The department has a colloquium series in which both senior and junior faculty from around the country travel to Rochester to give a seminar and meet with faculty and students. William Evan Johnson, PhD Associate Professor, Biostatistics - Boston University School of Public Health (617) 638-5847. Open J Stomatol. Associate Professor, Computational Biomedicine, Medicine, Boston University School of Medicine. Division of Computational Biomedicine, Boston University. Methodology: Bayesian methods, factor analysis and structural equations models, Hidden Markov models, dynamic programming, nonparametric regression, mixture models, high-performance and parallel computing, and Bayesian networks. I have got currently one Affybatch object by reading all the .cell files. Computational Biomedicine, Boston University. Evan is the Co-Director of the Single Cell Sequencing Core, and serves in the following capacities as well: Associate Professor of Medicine and Biostatistics; Education. 2020 03 05; 21(1):57. Author: W. Evan Johnson (Boston University), Marc-Danie Nazaire (Broad Institute) Contact: The ComBat discussion & help forum. N—Luke Wakehouse 2 run (kick failed), 5:01. PMID: 32071385 PMCID: PMC7431382 (available on … Statistical innovation focuses on the development of clinically motivated tools that integrate linear modeling, Bayesian methods, factor analysis and structural equations models, Hidden Markov models, mixture models, dynamic programming, and high-performance parallel computing. Appetite. Students can find additional information in the Undergraduate Student Guide and Graduate & Professional Student Guide. Background: Combining genomic data sets from multiple studies is advantageous to increase statistical power in studies where logistical considerations restrict sample size or require the sequential generation of data. PMID: 32401417. Mathematics & Statistics, CAS. ... Terrier Temp - Admin, Biostatistics - Boston University School of Public Health (617) 358-2936. icampbe1@bu.edu. W. Evan Johnson Associate Professor of Medicine and Biostatistics. William Evan Johnson, PhD - Boston University Medical Campus We would like to thank Dr Solaiappan Manimaran for insightful discussions throughout the development of this method. Am J Clin Nutr. Exploring changes in the human gut microbiota and microbial-derived metabolites in response to diets enriched in simple, refined, or unrefined carbohydrate-containing foods: a post hoc analysis of a randomized clinical trial. Stefano Monti. Babbs RK, Beierle JA, Yao EJ, Kelliher JC, Medeiros AR, Anandakumar J, Shah AA, Chen MM, Johnson WE, Bryant CD. McQuerry JA, Jenkins DF, Yost SE, Zhang Y, Schmolze D, Johnson WE, Yuan Y, Bild AH. Genome Biol. University of Wyoming; Daniel J … Computational Biomedicine, Boston University. Ruan QT, Yazdani N, Reed ER, Beierle JA, Peterson LP, Luttik KP, Szumlinski KK, Johnson WE, Ash PEA, Wolozin B, Bryant CD. * Correspondence: cjhong@bu.edu; wej@bu.edu †Equal contributors 1Computational Biomedicine, Boston University School of Medicine, 72 E Concord St. E645, Boston, MA 02118, USA 2Bioinformatics Program, Boston University, Boston, MA 02125, USA Full list of author information is available at the end of the article University of Pennsylvania ... Evan Johnson. The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View. However, significant technical heterogeneity is commonly observed across multiple batches of data that are generated from different processing or reagent … The focus of his group's research is to develop computational and statistical tools to investigate core components that contribute to disease prognosis and etiology, and for the accurate determination of optimal diagnostic, prognostic, and therapeutic regimens for individual patients. Bottom, left to right: Evan Bailey (team coach), Zach Missan, Greg Ginther, Brandon Xavier Frank, and Evan Johnson. Students can find additional information in the Undergraduate Student Guide and Graduate & Professional Student Guide. South 30, North 6. High-throughput data are now commonly used in molecular biology to (i) identify genomic features associated with outcomes and (ii) build signatures for prediction. FASEB J. Two teams from BU Law competed in the ABA Section of Labor and Employment Law’s 13th Annual Law Student Trial … Brown Paper Tickets - The first and only fair trade ticketing company! He has published in the journals Cell, Proceedings of the National Academy of Sciences, Biometrics, Nature Reviews Genetics, Annals of Applied Statistics, and Biostatistics. Evan Johnson and Camron Bryant is featured in BU Today. View Profile . Xavier JB, Young VB, Skufca J, Ginty F, Testerman T, Pearson AT, Macklin P, Mitchell A, Shmulevich I, Xie L, Caporaso JG, Crandall KA, Simone NL, Godoy-Vitorino F, Griffin TJ, Whiteson KL, Gustafson HH, Slade DJ, Schmidt TM, Walther-Antonio MRS, Korem T, Webb-Robertson BM, Styczynski MP, Johnson WE, Jobin C, Ridlon JM, Koh AY, Yu M, Kelly L, Wargo JA. Clin Infect Dis. Complex biological systems can be understood by dividing them into hierarchies. February 13, 2015 ~ W. Evan Johnson, PhD, Assistant Professor of Medicine, Boston University School of Medicine ~ “Efficient computational strategies for metagenomic profiling using unassembled sequencing data”. A Parsimonious Host Inflammatory Biomarker Signature Predicts Incident TB and Mortality in Advanced HIV. Summa Cum Laude in Mathematics, Southern Utah University. 10 Department of Neurology and Alzheimer's Disease Center, Boston University School of Medicine, Boston, MA, USA. Evan has 6 jobs listed on their profile. While several algorithms have been developed to perform … Biomarker Generation SCAN-UPC: Single Sample of Expression Estimates Biomarker and Personalized Medicine Work ows W. Evan Johnson (Boston University) Multiomic Biomarker Validation April 29, 2013 11 / 25. Their work includes a balance between statistical methods development, algorithm optimization, and clinical application. South 0 13 3 14—30. PMID: 32138770. PMID: 31761933. The third result is Evan M Johnson age 30s in Kansas City, KS. Buwembo W, Munabi IG, Kaddumukasa M, Kiryowa H, Nankya E, Johnson WE, Okello E, Sewankambo N. Periodontitis and Rheumatoid Arthritis in sub-Saharan Africa, gaps and way forward: a systematic review and meta-analysis. PMID: 31488082. Single-cell RNA-seq (scRNA-seq) has emerged as a powerful technique to quantify gene expression in individual cells and is being used to elucidate the … Being new to Affymetrix analysis, any advice/elaboration will be very helpful. Leong S, Zhao Y, Ribeiro-Rodrigues R, Jones-López EC, Acuña-Villaorduña C, Rodrigues PM, Palaci M, Alland D, Dietze R, Ellner JJ, Johnson WE, Salgame P. Cross-validation of existing signatures and derivation of a novel 29-gene transcriptomic signature predictive of progression to TB in a Brazilian cohort of household contacts of pulmonary TB. 2020 03; 6(3):192-204. Member, BU-BMC Cancer Center, Boston University. W. Evan Johnson Departments of Biostatistics and Medicine. They have successfully applied their tools in several biomedical and clinical scenarios, ranging from mechanistic studies and to precision genomics. ComBat-Seq: batch effect adjustment for RNA-Seq count data Yuqing Zhang1,2, Giovanni Parmigiani3,4, and W. Evan Johnson 1,2,5 1Division of Computational Biomedicine, Boston University School of Medicine 2Graduate Program in Bioinformatics, Boston University 3Department of Data Sciences, Dana-Farber Cancer Institute 4Department of Biostatistics, … in Statistics, Brigham Young University W. Evan Johnson - Associate Professor of Medicine & Biostatistics - Boston University School of Medicine | LinkedIn. Thomas Little. Medicine and Biostatistics, MED. The association between maximum measured work-shift Wet Bu... View. 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